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Giudice, A., Arra, C

Hernaez, A

References Bankhead, C

Taken together, these two compounds may complement one another instead of forcing you to choose between NAC vs NAD: NAC protects cells, while NAD drives energy and repair

In terms of its effects, it appears to impact drinking in ways (though not necessarily mechanisms) similar to naltrexone (FDA-approved) and topiramate (prescribed off label for alcohol use disorder), which have a greater effect in reducing intensity of drinking on drinking days relative to their effects on whether someone drinks at all (i.e., abstinent days) although all of them do increase abstinent days to some degree on average)

Progesterone has anti-inflammatory and mast cell stabilising properties, and some women find that including progesterone in their HRT helps with histamine-related symptoms