In a double-blind study of 45 healthy human subjects, gastric mucosa and gastric juice was found to be among the largest depots of ascorbic acid, with 25 times the serum concentration (Table 1) [196]
At present, relevant studies have confirmed that the expression of ALOX12 can reasonably predict the prognosis of patients, and ALOX12 can be used as a predictor of tumor prognosis [36,37,38]
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10.1016/j.tjog.2015.07.004 157
However, studies with transfected Chinese hamster ovary cells suggest that the type-2 isozyme may actually have a neutral pH optimum in its native state, and that the acidic optimum described may actually be an artifact of cell lysis 15