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Description

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Wojtas A, Bysiek A, Wawrzczak-Bargiela A, Szych Z, Majcher-Malanka I, Herian M, et al

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Nave (non-infected) erythrocytes and Plasmodium falciparum 3D7-infected erythrocytes were cultured at 37C, in low oxygen conditions (1% O 2 , 5% CO 2 , 94% N 2 ), at 4% or 0.4% hematocrit, in incomplete RPMI media (iRPMI: RPMI 1640 HEPES, 50 mg/L hypoxanthine, 10 mg/L gentamicin, pH 6.74), complete RPMI media (cRPMI: incomplete RPMI supplemented with 2.25 g/L sodium bicarbonate and 5 g/L AlbuMAX II), or Ringer solution (1mM CaCl 2 , 5mM glucose, 32 mM HEPES pH 7.4, 5 mM KCl, 1mM MgSO4, 125mM NaCl)

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It was found that liraglutide 3.0 mg daily caused a mean weight loss of around 8% at week 52 of the trial, while semaglutide 0.2 mg, 0.3 mg, and 0.4 mg caused an average weight reduction of between 11 to 14%

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