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Further mechanistic studies revealed that EGCG-Zn achieves synergistic anti-inflammatory and repair effects by inhibiting MAPK signaling-mediated inflammation and apoptosis, and by activating the Rap1 pathway, which regulates mucosal barrier repair

Association between a single nucleotide polymorphism in the 3-UTR of ARHGEF18 and the risk of nonidiopathic pulmonary arterial hypertension in Chinese population

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and reduced SIRT1 expression accompanied by miRNA alterations (Cho et al., 2015