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Specifically, future work should prioritize conducting specific animal studies to validate the hypothesized anti-fibrotic and anti-cancer effects of GLP-1 RAs in ALD and MetALD models

BENEFITS & CLINICAL TRIALS The primary research focus is the acceleration of recovery and healing of soft tissue and the reduction of inflammation

Htike ZZ, Zaccardi F, Papamargaritis D, Webb DR, Khunti K, Davies MJ

Dosing in these models mirrors the soft tissue range, supporting the use of similar protocols for fractures as for tendon injuries

Additionally, the suppression of pro-inflammatory cytokines (e.g., TNF-, IL-6) and inflammatory pathways, including the blocking of NF-B activation [39, 91], contributes to the establishment of an anti-inflammatory environment that can mitigate oxidative stress and inflammation induced muscle protein catabolism, thereby supporting the preservation of SMM and functional capacity [40]

Comparison of hematological parameters and biochemical parameters pre and postintervention between two groups of study are shown in Fig