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Stress & Cortisol Regulation Research indicates DSIP may modulate ACTH and cortisol secretion, helping explore hypothalamic-pituitary-adrenal (HPA) axis regulation [2]

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People who regularly take metformin, proton pump inhibitors, and H2 blockers, or have gastrointestinal disease are also at increased risk

Chicken, fish, legumes, and fortified grains all release nicotinamide during digestion