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In a study of 10 obese participants without diabetes and 10 controls who were given metformin 2.55g/d for two weeks, GLP-1 levels at 30 and 60 minutes after a glucose load were increased though baseline GLP-1 levels (and leptin) were unchanged on metformin 13

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NAC works on a slightly different timeline, supporting the steady, ongoing synthesis of glutathione within the liver and other tissues

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