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Cysteine Substrate Shortage: Oxidative stress prematurely converts cysteine, the rate-limiting GSH precursor, into inactive forms

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Studies show that quercetin upregulates the expression of the ABCG2 transporter (which helps remove uric acid) while blocking URAT1 and GLUT9 (which keep uric acid in your blood) [5]

Walker EF, Brennan PA, Esterberg M, Brasfield J, Pearce B, Compton MT

doi: 10.1016/j.ajem.2016.03.021

(2010) Arabidopsis GLUTATHIONE REDUCTASE1 plays a crucial role in leaf responses to intracellular hydrogen peroxide and in ensuring appropriate gene expression through both salicylic acid and jasmonic acid signaling pathways