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Clinica Chimica Acta: International Journal of Clinical Chemistry, 333 (1), 1939

Furthermore, children with IGF-1 deficiency-primary GH insensitivity or children with Laron syndrome who were treated with biosynthetic IGF-1 (165) showed increases in their serum alkaline phosphatase and serum procollagen and IGF-binding protein-3 (IGFBP-3) (165167)

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Therefore, the effect of G6PD enzyme deficiency leading to NADPH insufficiency is particularly marked in the RBC