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PLoS One 14:e0221828

A Review of Vitamin B12 in Dermatology. American Journal of Clinical Dermatology, vol

23 : 13121318 Jeulin C, Soufir JC, Marson J, Paquignon M, Dacheux JL

Lorenza R, Armando S

GLP-1R agonists may exert antidepressant effects by modulating inflammatory processes in the brain Chronic inflammatory processes in the brain associated with excessive activation of microglia and increased production of pro-inflammatory cytokines are one of the key factors leading to the development of depressive symptoms, as patients suffering from this mental illness are very often characterized by elevated levels of tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), interleukin-1 beta (IL-1), C-reactive protein (CRP), and interferon-gamma (IFN-) in the cerebrospinal fluid and the blood [59,60,61]

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