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This may include instances where: You need a stronger product to achieve your goals (e.g., deep hyperpigmentation, severe acne, etc.) You already use another product containing copper (this could be unsafe) An essential part of your skin care routine is a harsh active, vitamin C, strong exfoliant, or salicylic acid many of which are common ingredients in acne treatments and anti-aging products (copper peptides shouldnt be mixed with them) Using copper peptides may be unsafe (i.e., you have Wilsons disease, a peptide allergy, or active/suspected cancer) Youve tried a copper peptide product in the past and experienced an adverse reaction (e.g., copper uglies or troublesome side effects) If youd like some alternatives to copper peptides, we go over a few in the Alternatives to copper peptide serums section later in this guide
Cao S, Yan B, Lu Y, Zhang G, Li J, Zhai W, Guo W, Zhang S
reduced glutathione (GSH) is the active form that is able to repair oxidative damage, and oxidized glutathione (GSSG) is the inactive form that can be recycled back into GSH
Combining both peptides Some formulations include both AHK-Cu and GHK-Cu, attempting to capture benefits from each
Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications