During **deep slow-wave sleep, brain cells temporarily shrink, allowing cerebrospinal fluid to flow more freely and wash away waste products, including amyloid-beta, a protein linked to Alzheimer's disease
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for mechanistic isolation, the choice depends on which pathway is being studied
doi: 10.1016/j.nbd.2013.01.018 117 KartenB.CampenotR
[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Koellhoffer EC, McCullough LD, Ritzel RM
NNMT inhibitors NNMT has garnered significant attention due to its role in various metabolic processes and its potential as a therapeutic target 195