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1 How Do GLP-1 Medications Work

Common causes: diabetes, hypertension, chronic glomerulonephritis, polycystic kidney disease

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As CCKR signaling can stimulate increases in intracellular calcium (Ca 2+ ) in rat islets and other cell types 21,29,30 and this could be the trigger for insulin secretion in a -cell, we measured cytosolic Ca 2+ in -cells of isolated mouse islets before and after the addition of 1 M CCK