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These medications, including Ozempic, Wegovy, and Mounjaro, work by mimicking a natural hormone that helps regulate blood sugar and appetite

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Constipation, while less common than diarrhea, may also occur and can be particularly problematic in patients with pre-existing constipation issues

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The refined models exhibited good model-density fitting and model geometry (see Supplementary information, Table S1 for data and model refinement statistics)

The lack of insulinotropic response to GIP has long been claimed as the reason for not targeting the GIP receptor in this patient group