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A score of 1 was assigned if fluorescence was visible within the cytosol, while a score of 0 was assigned if fluorescence was present in the nucleus but the cytosolic signal failed to exceed that of the age-matched, non-transgenic N2 worms

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Supporting this, data from our functional enrichment analysis of the transcriptome revealed notable upregulation of oxidative phosphorylation and the oxidative damage response in hepsin / mice treated with saline (data not shown)

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