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Evidence points to both central and peripheral proinflammatory mechanisms working alone or together with neurotoxic molecules, such as NH3.59,60 In turn, hyponatremia, sepsis, gastrointestinal bleeding, and kidney failure precipitate the exogenous production of TNF, which exacerbates HE presentation
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Potential Side Effects and Precautions Common Side Effects While MIC B12 injections are generally well-tolerated, some individuals may experience mild side effects
Common side effects may include: Nausea, vomiting, diarrhea, constipation, or indigestion Abdominal discomfort or bloating Injection site redness or irritation Fatigue related to nausea Occasional belching or heartburn Most side effects are mild and temporary, improving as your body adjusts to the medication
(2021) Cell Metab 33, 174-189.e7