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In animal models, it has shown potential in accelerating the healing of wounds, promoting the outgrowth of tendon fibroblasts, and cell survival under stress [3]

However, the authors included only six RCTs involving tirzepatide and, as opposed to our meta-analysis, did not provide information on comparative effects across different doses of the two medications [55]

When used together, there may be an additive effect on heart rate , which could be clinically significant in patients with pre-existing cardiovascular conditions, including hypertension, arrhythmias, or coronary artery disease

Semaglutide and Tirzepatide show the most promising results, while options like Liraglutide and Exenatide remain valuable for their safety and efficacy

[1] [3] Additional contraception is not routinely required solely due to semaglutide use

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