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Some individuals report feeling overstimulated with high-dose supplementation, though these reports are anecdotal and not supported by controlled studies

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doi: 10.1016/j.cmet.2022.11.005 Summary Keywords Sjogrens syndrome, mitochondria, mitochondrial metabolism, immune cell, transcriptomics, RNA sequencing Citation Luo D, Li L, Wu Y, Yang Y, Ye Y, Hu J, Gao Y, Zeng N, Fei X, Li N and Jiang L (2023) Mitochondria-related genes and metabolic profiles of innate and adaptive immune cells in primary Sjgrens syndrome

Bakan E, Taysi S, Polat MF, Dalga S, Umudum Z, Bakan N, et al

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Magness performed a treadmill test before and after the infusion, calling the results "almost unbelievable," and causing Salazar to email disgraced cycling star Lance Armstrong, "Lance call me asap