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Exercise in combination with GLP-1 medications appears to enhance the GLP-1 function leading to better sugar control in type 2 diabetics, though the exact way it works is not clear [16]

This is consistent with the observed I/III RS overactivity seen in fibroblast culture

Moreover, studies suggest that dual and triple receptor agonists may have additional effects on histological NASH features vs high-dose GLP-1R agonists alone, and that these may be independent of changes in body weight [78]

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Stomach Semaglutide slows gastric emptying, or the rate at which food moves out of the stomach and into the small intestine

Documentation Summary for CDI Obesity Encounter Checklist For additional guidance on obesity coding, refer to the FY2026 ICD-10-CM Official Guidelines (CMS), the AHA Coding Clinic, and the American Society for Metabolic and Bariatric Surgery (ASMBS) clinical guidelines