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Phase IIb Results and Regulatory Status A larger Phase IIb trial involving over 500 overweight and obese subjects was conducted to further evaluate efficacy and safety
The number of injections and frequency of them will vary from person to person
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Common neurological manifestations include: Paraesthesia (pins and needles) in the hands and feet Numbness and altered sensation Difficulty with balance and coordination (ataxia) Memory problems and cognitive impairment Mood changes, including depression and irritability In severe cases, visual disturbances and confusion These neurological features arise from demyelination of peripheral nerves and the spinal cord, a condition known as subacute combined degeneration when it affects the posterior and lateral columns of the spinal cord
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