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El Hajj C, Fares S, Chardigny JM, Boirie Y, Walrand S

Fistulas are a major Crohns disease complication, and this is one of the more clinically relevant preclinical findings

Repeatedly injecting in the same location can lead to lipohypertrophy, a condition characterized by lumpy, thickened areas of fatty tissue that can impair medication absorption and lead to unpredictable blood glucose levels

The presence of multiple smaller peaks indicates impurities, which could be truncated sequences, non-target modifications from synthesis, or residual reagents

That difference defines everything: the side effect profiles, who can use each, and whether they belong in the same routine

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