In sum, current evidence positions GLP-1 RAs as a potential cardioprotective strategy in HF, with HF with preserved ejection fraction emerging as the clinically most relevant phenotype for the drug class, especially when occurring in people with obesity with and without diabetes
Prandial insulin may be considered in patients resistant to other treatments, and if so, will often only be used with the largest meal initially
Tirzepatide effectively attenuated the rewarding properties of alcohol as measured through locomotor stimulation, conditioned place preference, and accumbal dopamine release
Fat cells produce estrogen, and too much of the hormone can negatively impact the function of the ovaries or the endometrial lining
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