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For weight loss, semaglutide supports a steady calorie reduction without requiring extreme dietary changes

Future investigations should leverage the pleiotropy of GLP-1RAs to evaluate their effectiveness in treating multimorbidities, rather than focusing on a single health condition, particularly where obesity or other mechanistic pathways affected by GLP-1RAs are leading drivers, the authors write in their paper

They actually found small increases in several musculoskeletal problems

The drug received FDA approval for the treatment of obstructive sleep apnea in 2024

F., Mahmoudi M., Wang Z., Wang R

Which of the Millennial "who's who" in Hollywood have gone the GLP-1 route