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doi: 10.1038/s41586-018-0119-x 157 Rufino-RamosD.AlbuquerqueP

10.1007/s00401-013-1148-z Acta Neuropathol

Visible transformation: Brighter skin in 514 days

The 6-month wait is outdated and harmful : Current guidelines requiring 6 months of behavioral therapy before medication lead to high dropout rates (53-70% of early non-responders fail to achieve 5% weight loss) and treatment abandonment

Clinical studies have shown that patients can expect significant weight loss (around 5-10% of their body weight) after about 6 months of consistent use, although individual results may vary based on lifestyle factors such as diet and exercise

An Pediatr