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Recombinant FcRn Truncated soluble and Glutathione S-transferase (GST) tagged human FcRn lacking the transmembrane domain (hFcRn-GST) was produced in HEK293E cells and purified on a GSTrap column (Cytiva Life Sciences) 67

In the LPS-induced acutelung injury mouse model, treatment of GHK-Cu also significantly suppressed TNF- and IL-6 expression with a significant decrease of both NF-B p65 and p38 MAPK signaling, suggesting that GHK-Cu is useful for the development of novel anti-inflammatory therapies [22]

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Brain Behav Immun 87:901909 Poljsak B, uput D, Milisav I (2013) Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants