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These results are clinically relevant to actively growing children that may require therapeutic intervention using angiogenesis inhibitors to prevent unwanted formation of new blood vessels, such as in pediatric cancers

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To measure saturation binding for FITC- or TMR-labelled exendin-4 and exendn-4-C16 directly, these ligands were added to cells and incubated as above, followed by measurement of TR-FRET signal using the following settings: FITC ligands: ex 340 nm, em 520 and 620 nm, auto-cutoff, delay 50 s, integration time 300 s

Del Vecchio, F

and Danielle Schupp, registered dietitian and sports nutritionist.

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