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Slower dose escalation and dietary changes accelerate this process

All documented observations remain confined to investigational, analytical, and preclinical laboratory contexts and are presented solely for exploratory scientific research purposes

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We estimated the percent mediation of the change in eGFR at week 104, potentially attributable to change in weight, by assessing how much the treatment effect on eGFR was altered by including the weight change in the regression model adjusted for baseline eGFR and baseline weight

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