Magnesium symptoms of magnesium deficiency include irritability, difficulty with concentration, insomnia, depression, and anxiety
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Anxiety-like symptoms have also been reported by some individuals at these higher doses, though the mechanism is not fully understood
SGLT2is, such as empagliflozin and canagliflozin, are well-established for their ability to reduce albuminuria, slow the decline in eGFR, and lower the risk of CV events in diabetic patients with CKD
For higher-risk patients, repeat FBC and iron studies (serum ferritin, serum iron, transferrin saturation) at 3-6 month intervals may be appropriate
Its also worth noting that side effects often get better over time