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Pregnancy: Insufficient safety data

11 These researchers transitioned patients who were reasonably well controlled (A1c 7.5% or less) from bolus insulin to a GLP-1 RA (semaglutide) in a one-step approach

AOD9604 alone significantly improved both gross morphological and histopathological cartilage scores versus saline controls, and the combination of AOD9604 with hyaluronic acid produced superior outcomes to either agent administered alone including significantly shorter lameness periods

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PloS One (2019) 14(1):e0202458

If a molecule were in the "D-form" (right-handed), your body likely wouldn't be able to use it for its intended purpose