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Signalling mechanism for somatostatin receptor 5-mediated suppression of AMPA responses in rat retinal ganglion cells

That will change when results of the phase 3 randomized SELECT trial (NCT03574597) are released, perhaps as soon as 2023 or early 2024

Nature 379: 69-72, 1996

The drug seems to turn the bodys metabolic gears by targeting pathways associated with fat utilization and glucose regulation

Time-sensitive dosing : A gap in treatment requires starting at the lowest dose again, increasing the time to reach therapeutic levels

However, minor variations in blood flow around these areas, plus the amount of fat present, can mean you absorb the medication at different rates