In this trial, semaglutide was given at 1 mg, the maintenance dose studied at the time
These patients will have a difficult time absorbing B12 unless they have appropriate amounts of stomach acid and HCL
Supplementary Table S1) 215
These drugs copy a hormone which boosts insulin release, decreases glucagon, and slows the gastric emptying process
That said, not everyone will have better results on Zepbound
Moreover, microbial transplantation studies in germ-free mice with human commensals containing a functional (but not a deletion mutant) microbial cutC gene (responsible for cholineTMA transformation) (23) and genetic manipulation (both gain of function and loss of function) of host hepatic flavin monooxygenase 3 have been shown to modulate host TMAO levels, platelet responsiveness, and thrombosis potential in vivo (24)