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Tanvir, Z., Nelson, R., DeCicco-Skinner, K

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2020 Jan;102:106675

154,155 PTEN is an ASD risk gene located on chromosome 10q23 that encodes a lipid specific for phosphatidylinositol (3,4,5)-triphosphate (PIP3), which is a negative regulator of PI3K/AKT/mTORC1 signalling upstream of TSC1/TSC2, resulting in symptoms of ASD

I used to be very weak, my entire body used to hurt (especially the lower back and arm), but not anymore