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Studies comparing the combined therapy to individual medications found greater reductions against SGLT2is than GLP1-RAs

Dosing and Administration: What the Protocol Actually Looks Like Both medications are administered via weekly subcutaneous injection a small, pre-filled auto-injector pen that most patients find far less intimidating than anticipated

As patients and clinicians navigate treatment with this newer agent, questions arise about its composition and potential nutritional implications

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When the pH in the duodenum (small intestine) reaches 2 4.5 (acidic) or encounters amino acids from protein digestion, secretin is released by cells in the small intestine which triggers bicarbonate release

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