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Orlistat is a prescription medication produced by two pharmaceutical companies in the UK and is suitable for long-term use, especially for those seeking a less potent, non-injectable option

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As expected 6 , PDS5B depletion led to HR deficiency that could be complemented by ectopic expression of PDS5B WT , but expression of PDS5B 17A was ineffective in this regard although the decrease in HR was less severe than that observed with knockdown of BRCA2 (Supplementary Fig