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This will help them adjust the medication dosage to fit the patient's needs better

Allopurinol, the first-line ULT, suffers from reduced efficacy in patients with impaired conversion to its active metabolite, oxypurinol (OXY), and carries risks of severe hypersensitivity reactions (Yi et al., 2024)

Similar to a histamine elimination diet, doing a trial with a DAO supplement may give you good information

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Front Pharmacol 12:660083 Rahman I, Adcock IM (2006) Oxidative stress and redox regulation of lung inflammation in COPD

This is why a muscular person could be considered overweight, whereas someone with a normal BMI may have high body fat, which is linked to risks like type 2 diabetes or impaired glucose (Salmon-Gomez et al 2023)