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The regulation of Ca signaling in astrocytes is primarily mediated by inositol trisphosphate receptors (IP3Rs), which have been studied for their potential roles in brain damage and neuronal death in mouse models 100

Importantly, the various diets contained identical fiber and protein content and varied primarily by the percentage of fat- and carbohydrate-derived kilocalories

The dimer form of 6-thio-dG shows strong potential to enhance chemotherapeutic efficacy by effectively inhibiting GSTP1 and overcoming drug resistance

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It is also important for releasing energy from food and using vitamin B11 (folic acid)