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The wide range reflects individual variation in requirements and the difficulty of over-dosing b12

Common amounts: 1 mL, 2 mL, 3 mL, 5 mL Results Concentration 2.500 mg/mL Draw volume per dose 0.200 mL On U-100 insulin syringe 20.0 units Approx

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Real-world response rates have generally been reported to be higher than those achieved in clinical trials, which may be related to factors such as dose escalation and less refractory patient cohorts than those participating in clinical trials

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