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Keep the cap tightly closed after opening

20 , e83e89 (2020)

How Diphenhydramine Acts on the Brain and Body The chemical structure of diphenhydramine allows it to cross the blood-brain barrier and interact with histamine receptors in the brain, causing sedation or drowsiness

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obtaining or self-administering it outside this framework falls outside UK medicines regulations

When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention