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Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells

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The article says patients with type 2 diabetes, a high baseline BMI, or insulin resistance often experience more dramatic loss initially, with a baseline BMI above 35 associated with higher absolute loss potential

doi: 10.1038/s41401-020-0439-x 147 WangQBinCXueQGaoQHuangAWangKet al

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Several studies and reviews have found that L-Carnitine supplementation can produce modest reductions in body weight and fat mass, particularly in overweight or obese individuals, and especially when combined with structured exercise programs