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Patel AJ, Liao CP, Chen Z, Liu C, Wang Y, Le LQ

It is tempting to speculate that this apparent loss of benefit in patients with more advanced HF may be the result of increases in HR caused by activation of sinoatrial node (SAN) GLP-1Rs (64, 65), which could be mitigated with an agent such as GLP-1(2836) that retains cardiac and vascular protection of GLP-1, without activating the GLP-1R

Taking vitamin C supplements can have the same effect

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For lupus patients already managing neuropsychiatric symptoms, any new mood disturbance should be evaluated carefully

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