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Thus, TLR2/TLR4 activation promotes the dissociation of the inhibitor of nuclear factor kappa-B (I-B)/NF-B complex through a myeloid differentiation primary response 88-dependent (MyD88) signaling pathway, mediating the nuclear translocation of nuclear factor kappaB (NF-B) and specifically acting on the NLRP3 and IL-1B gene promoter regions

This side effect can be linked to the dizziness and fatigue caused by gabapentin

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Higher rates of toxicity were reported in patients receiving ramucirumab treatment (Mackey et al., 2015)

Glioblastoma is the most aggressive primary brain tumor with extremely poor prognosis despite multimodal treatment including surgery, radiation, and chemotherapy

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