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For example, in case of MECP2 , it may be preferable to induce moderate activation through the traditional dCas9-VP64 instead of the more robust activators as over-activation of MECP2 could potentially result in MDS

Sensitization of prostate cancer to radiation therapy: molecules and pathways to target

SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies

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Cell 181(2):271-280.e8 Muus C, Luecken MD, Eraslan G, Waghray A, Heimberg G, Sikkema L et al (2020) Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

Castro-Gago M, Eiris-Punal J, Novo-Rodriguez MI, et al