Earlier this month, (June 2025), Novo inked a deal worth up to $815 million with Deep Apple Therapeutics, a South San Francisco-based company specializing in small-molecule drug discovery to discover, develop, and commercialize oral small-molecule therapeutics directed at a non-incretin G protein-coupled receptors (GPCR) target for cardiometabolic diseases, including obesity, in a deal worth up to $812 million
Jiang ZG, Feldbrgge L, Tapper EB, Popov Y, Ghaziani T, Afdhal N, et al
According to the MHRA-approved SmPC, the standard titration schedule is as follows: Weeks 14 : 0.25 mg once weekly (starting dose) Weeks 58 : 0.5 mg once weekly Weeks 912 : 1 mg once weekly Weeks 1316 : 1.7 mg once weekly Week 17 onwards : 2.4 mg once weekly (maintenance dose) At week 3, patients remain on the 0.25 mg dose
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