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10.1172/JCI111682

Nat Biotechnol

Because the peptide occurs naturally in human plasma (at roughly 200 ng/mL in young adults, declining to approximately 80 ng/mL by age 60), topical supplementation essentially restores youthful local concentrations in treated skin

Diabetes Rep

Activated caspase-1 fosters inflammation through several pathways: (1) it facilitates the maturation and release of proinflammatory cytokines (IL-1 and IL-18)