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Notably, oxidative phosphorylation efficiency at complexes I and IIspecifically when glucose was the fuel sourceemerged as a stronger predictor of GWS severity than markers of peripheral inflammation

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Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial

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The extensive SUSTAIN program validated significant reductions in HbA1c levels and weight loss compared to other treatments, as well as a 26% decrease in the relative risk of major adverse cardiovascular events (SUSTAIN-6)