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Estos medicamentos requieren capacitacin adecuada para su uso correcto

Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks

Clinical trial data have generated significant interest in retatrutide because of its substantial weight-loss results, including Phase 3 findings showing average body weight reductions of more than 30% at the highest studied dose over 80 weeks

Un estudio clave en este campo es el ensayo SCALE (Satiety and Clinical AdiposityLiraglutide Evidence) que evalu el impacto de la liraglutida (liraglutide), un anlogo de GLP- 1, en individuos con obesidad

Retatrutide, developed under the code LY3437943, is a synthetic single-chain peptide engineered to act as an agonist at three receptors at once: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)

People who take regular doses of semaglutide or tirzepatide (another active ingredient in some GLP-1 meds) can buy the brand-name drugWegovy, Ozempic, Zepbound, Mounjarothrough a regular pharmacy, if covered by health insurance, or directly from the manufacturer