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Both drugs target different pathways in glucose regulation and appetite control, and early clinical trial data suggests their combined effect exceeds what either drug achieves alone

Who should consider tirzepatide with B12 and who should avoid it Ideal candidates for tirzepatide with B12 include adults with obesity (BMI 30) or overweight with comorbidities (BMI 27 with conditions like type 2 diabetes, hypertension, or dyslipidemia)

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