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Nanoformulation for enhanced drug delivery and better patient compliance

RV-8451, differentiated oral, muscle-preserving GLP-1 candidate for obesity Recent Highlights: In February 2026, Rivus stated it was entering a pivotal year, advancing HU6 in the AMPLIFY Phase 2 MASH trial while preparing the first clinical trial for RV-8451, its muscle-preserving oral GLP-1 candidate, designed to address the muscle-loss criticism leveled at existing GLP-1 therapies

Shaharyar Khan, PhD, Chief Scientific Officer Number Of Employees: ~27 Stage: Private, Series B2 Financial Snapshot: Has raised $224M total across funding rounds, including a $132M Series B Notable Investors: RA Capital Management

By lying down, it causes the food to stay in the stomach longer, which will trigger more nausea and acid reflux. Admittedly, its all too easy to watch Netflix in bed after eating dinner

Pendulum appears to perform solidly in all four aspects

These structural refinements result in a half-life of approximately 160 h, enabling once-weekly subcutaneous administration while maintaining effective glycemic control (Fig