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In the BM assay, mice were required to locate an escape box placed at the target hole using spatial cues during days 1-4 of the acquisition phase

Compound 29 also demonstrated potential in vivo blood glucose-lowering efficacy in male Wistar rats (104)

The unmodified amylin backbone binds amylin receptors but lacks the pharmacokinetic profile necessary for studies requiring sustained receptor occupancy over hours or days

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