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Participants saw better blood sugar levels and lipid profiles

JAMA Netw Open 2022;5:E221169

Physical performance Ask whether the patient is: Walking more slowly Avoiding stairs Struggling to rise from a chair Falling or nearly falling Losing independence with daily activities Unable to complete usual exercise Becoming progressively fatigued with routine tasks 5

There are strict eligibility criteria

Clin Drug Investig (2020) 40(8):695713

However, recent studies have highlighted that prorenin and/or active renin can bind to prorenin receptor (PRR), which is expressed in glomerular mesangial cells, collecting ducts, and the subendothelium of renal arteries